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dc.contributor.authorRoy, Biancafr
dc.contributor.authorSamson, Nathaliefr
dc.contributor.authorMoreau-Bussière, Françoisfr
dc.contributor.authorOuimet, Alainfr
dc.contributor.authorDorion, Dominiquefr
dc.contributor.authorMayer, Sandeepfr
dc.contributor.authorPraud, Jean-Paulfr
dc.date.accessioned2015-10-13T23:20:54Z
dc.date.available2015-10-13T23:20:54Z
dc.date.created2008fr
dc.date.issued2015-10-13
dc.identifierPMID:18703758fr
dc.identifier.urihttp://hdl.handle.net/11143/7960
dc.description.abstractThe present study stems from our recent demonstration (Moreau-Bussiere F, Samson N, St-Hilaire M, Reix P, Lafond JR, Nsegbe E, Praud JP. J Appl Physiol 102: 2149-2157, 2007) that a progressive increase in nasal intermittent positive pressure ventilation (nIPPV) leads to active glottal closure in nonsedated, newborn lambs. The aim of the study was to determine whether the mechanisms involved in this glottal narrowing during nIPPV originate from upper airway receptors and/or from bronchopulmonary receptors. Two groups of newborn lambs were chronically instrumented for polysomnographic recording: the first group of five lambs underwent a two-step bilateral thoracic vagotomy using video-assisted thoracoscopic surgery (bilateral vagotomy group), while the second group, composed of six lambs, underwent chronic laryngotracheal separation (isolated upper airway group). A few days later, polysomnographic recordings were performed to assess glottal muscle electromyography during step increases in nIPPV (volume control mode). Results show that active glottal narrowing does not develop when nIPPV is applied on the upper airways only, and that this narrowing is prevented by bilateral vagotomy when nIPPV is applied on intact airways. In conclusion, active glottal narrowing in response to increasing nIPPV originates from bronchopulmonary receptors.fr
dc.language.isoengfr
dc.relation.isformatofdoi:10.1152/japplphysiol.90727fr
dc.relation.ispartofISSN:8750-7587fr
dc.relation.ispartofJournal of applied physiologyfr
dc.subjectBronchopulmonary receptorsfr
dc.subjectVolume control ventilationfr
dc.subjectVideo-assisted thoracic surgeryfr
dc.subjectUpper airwaysfr
dc.subjectVagotomyfr
dc.titleMechanisms of active laryngeal closure during non-invasive intermittent positive pressure ventilation in non-sedated lambsfr
dc.typeArticlefr
dc.rights.holder© American Physiological Societyfr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.period105(5)fr
udes.description.sponsorshipCanadian Institutes of Health Researchfr
udes.description.sponsorshipFoundation of Starsfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationRoy, B., Samson, N., Moreau-Bussière, F., Ouimet, A., Dorion, D., Mayer, S., Praud, J.-P. (2008). Mechanisms of active laryngeal closure during noninvasive intermittent positive pressure ventilation in nonsedated lambs. Journal of applied physiology, 105(5), 1406-1412. doi:10.1152/japplphysiol.90727fr
udes.description.sourceJournal of applied physiologyfr
udes.autorisation.depottruefr
udes.description.ordreauteursRoy, Bianca; Samson, Nathalie; Moreau-Bussière, François; Ouimet, Alain; Dorion, Dominique; Mayer, Sandeep; Praud, Jean-Paul


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