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dc.contributor.authorDjeddi, Djamalfr
dc.contributor.authorCantin, Dannyfr
dc.contributor.authorSamson, Nathaliefr
dc.contributor.authorHao, Tianfr
dc.contributor.authorPraud, Jean-Paulfr
dc.date.accessioned2015-10-13T22:22:03Z
dc.date.available2015-10-13T22:22:03Z
dc.date.created2013fr
dc.date.issued2015-10-13
dc.identifierPMID:23535760fr
dc.identifier.urihttp://hdl.handle.net/11143/7952
dc.description.abstractObjectives: It is presently recommended that oral feeding be started in premature infants as soon as possible, often at an age at which nasal continuous positive airway pressure (nCPAP) is still required for ventilatory support. Our previous data showed that application of nCPAP up to 10 cmH2O in full-term lambs had no deleterious effect on cardiorespiratory safety, feeding efficiency, or on nutritive swallowing-breathing coordination. Besides fear of swallowing-breathing coordination disturbances, esophageal motility disruption by nCPAP could be a reason to delay oral feeding. To our knowledge, no study has focused on the effects of nCPAP on esophageal motility in the neonatal period. The aim of the present study was therefore to further assess the effects of nCPAP on oral feeding by assessing its effects on the esophageal phase of nutritive swallowing (nutritive esophagodeglutition). Methods: Six full-term lambs, ages 2 to 3 days, underwent esophageal multichannel intraluminal impedance-pH monitoring. Lambs were bottle-fed under 2 randomized conditions, namely spontaneous breathing and nCPAP 6 cmH(2)O. Results: Beyond confirmation of unaltered feeding efficiency, analysis of multiple variables measured by impedance monitoring revealed that nCPAP 6 does not alter nutritive esophagodeglutition in any way (nCPAP vs spontaneous breathing, P > 0.1 for all variables). Conclusions: offering further support to neonatologists pleading for initiation of oral feeding in infants still on nCPAP, the present results set the foundations for similar clinical studies in preterm human infants to confirm the absence of effects of nCPAP on nutritive swallowing.fr
dc.language.isoengfr
dc.relation.isformatofdoi:10.1097/MPG.0b013e318292b3b2fr
dc.relation.ispartofISSN:0277-2116fr
dc.relation.ispartofJournal of pediatric gastroenterology and nutritionfr
dc.subjectAnimal modelfr
dc.subjectEsophageal motilityfr
dc.subjectMultichannel impedance monitoringfr
dc.subjectNeonatesfr
dc.subjectSwallowingfr
dc.subjectVentilatory supportfr
dc.titleAbsence of effect of nasal continuous positive-airway pressure on the esophageal phase of nutritive swallowing in newborn lambsfr
dc.typeArticlefr
dc.rights.holderLippincott, Williams & Wilkinsfr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages1-12fr
udes.description.period57(2)fr
udes.description.sponsorshipCanada Research Chair in Neonatal Respiratory Physiologyfr
udes.description.sponsorshipCanadian Institutes of Health Researchfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationDjeddi, D., Cantin, D., Samson, N., Tian, H., Praud, J.-P. (2013). Absence of effect of nasal continuous positive airway pressure on the esophageal phase of nutritive swallowing in newborn lambs. Journal of pediatric gastroenterology and nutrition, 57(2), 188-191. doi:10.1097/MPG.0b013e318292b3b2fr
udes.description.sourceJournal of pediatric gastroenterology and nutritionfr
udes.autorisation.depottruefr
udes.description.ordreauteursDjeddi, Djamal; Cantin, Danny; Samson, Nathalie; Hao, Tian; Praud, Jean-Paul


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