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dc.contributor.authorDjeddi, Djamalfr
dc.contributor.authorSamson, Nathaliefr
dc.contributor.authorPraud, Jean-Paulfr
dc.contributor.otherBoudaa, Nadiafr
dc.date.accessioned2015-10-11T17:35:36Z
dc.date.available2015-10-11T17:35:36Z
dc.date.created2012fr
dc.date.issued2015-10-11
dc.identifierPMID:22722679fr
dc.identifier.urihttp://hdl.handle.net/11143/7946
dc.description.abstractWe aimed to determine whether the newborn lamb at term is a valid model for studying gastroesophageal reflux. Seven bottle-fed lambs, ages 2 to 3 days, underwent esophageal multichannel intraluminal impedance-pH monitoring (MII-pH). A total of 196 reflux episodes were recorded, including 73% alkaline and 27% weakly acidic. No acid refluxes were observed. Median bolus clearance time was 4  seconds (3; 5.5), and proximal reflux extent was 35% (26). This first report of MII-pH in the newborn mammal sets the foundations for future studies with physiological and clinical relevance to human neonates.fr
dc.language.isoengfr
dc.relation.isformatofdoi:10.1097/MPG.0b013e318263cae0fr
dc.relation.ispartofISSN:0277-2116fr
dc.relation.ispartofJournal of pediatric gastroenterology and nutritionfr
dc.subjectAnimal modelfr
dc.subjectEsophageal pHfr
dc.subjectMultichannel impedance monitoringfr
dc.subjectNeonatesfr
dc.titleThe newborn lamb as a new model for studying gastroesophageal refluxfr
dc.typeArticlefr
dc.rights.holder© Lippincott, Williams & Wilkinsfr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages1-11fr
udes.description.period55(6)fr
udes.description.sponsorshipCanadian Institutes of Health Researchfr
udes.description.sponsorshipCanada Foundation for Innovationfr
udes.description.sponsorshipCanada Research Chair in Neonatal Respiratory Physiologyfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationDjeddi, D., Samson, N., Boudaa, N., Praud, J.-P. (2012). Newborn lamb as a new model for studying gastroesophageal reflux. Journal of pediatric gastroenterology and nutrition, 55(6), 745-746. doi:10.1097/MPG.0b013e318263cae0fr
udes.description.sourceJournal of pediatric gastroenterology and nutritionfr
udes.autorisation.depottruefr
udes.description.ordreauteursDjeddi, Djamal; Samson, Nathalie; Boudaa, Nadia; Praud, Jean-Paul


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