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dc.contributor.authorPaquette, Benoitfr
dc.contributor.authorAli, Hasratfr
dc.contributor.authorLanglois, Réjeanfr
dc.contributor.authorVan Lier, Johannes E.fr
dc.contributor.editorUniversité de Sherbrooke. Laboratoire des sciences des radiationsfr
dc.date.accessioned2015-04-28T23:23:23Z
dc.date.available2015-04-28T23:23:23Z
dc.date.created1988fr
dc.date.issued2015-04-28
dc.identifier.urihttp://hdl.handle.net/11143/6760
dc.description.abstractWater soluble chloro aluminum phthalocyanines sulfonated to different degrees are studied for phototoxicity and cellular distribution in V-79 Chinese hamster cells. The more hydrophobic disulfonated dyes, with sulfonate substituents on adjacent benzyl groups of the phthalocyanine ring structure, exhibited the best cell penetrating properties and the highest phototoxicity. Fluorescence microscopy revealed that the dye was uniformly distributed in the cytoplasm but absent in the nucleus. The greater cell membrane penetrating properties of the lower as compared to the higher sulfonated dyes are attributed to the amphiphilic nature of the former.fr
dc.language.isoengfr
dc.relation.ispartofISSN:0031-8655fr
dc.relation.ispartofPhotochemistry and photobiologyfr
dc.subjectCellular distribution in Chinese hamster cellsfr
dc.titleBiological activities of phthalocyanines-VIII. Cellular distribution in V-79 Chinese hamster cells and phototoxicity of selectively sulfonated aluminum phthalocyaninesfr
dc.typeArticlefr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages215-220fr
udes.description.period47 (2)fr
udes.description.sponsorshipChinfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
udes.description.sourcePhotochemistry and photobiologyfr
udes.autorisation.depottruefr
udes.description.ordreauteursPaquette, Benoit; Ali, Hasrat; Langlois, Réjean; Van Lier, Johannes E.


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