RSS 1.0Publications et recherches – Médecine et sciences de la santé
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The effectiveness of transdiagnostic cognitive behavioural therapy for anxiety disorders: the role of and impact of comorbid depression
Other titre : Comorbid depression in tCBT for anxiety disorders(2023)Abstract: Transdiagnostic Cognitive Behaviour Therapy (tCBT), an intervention designed to be applicable across multiple diagnoses, was introduced to improve limitations in traditional therapy such as cost and access to ... -
Impact of group transdiagnostic cognitive-behavior therapy for anxiety disorders on comorbid diagnoses : results from a pragmatic randomized clinical trial in primary care
Other titre : Comorbid outcomes(2021)Abstract : Background: Anxiety and depressive disorders are the most common mental illnesses worldwide, with most individuals meeting criteria for more than one diagnosis. Most CBT approaches target only one disorder at a ... -
Phenotyping the Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA): protocol for an observational and translational pilot study
(2023)Abstract: Introduction Asthma and its associated exacerbation are heterogeneous. Although severe asthma attacks are systematically prescribed corticosteroids and often antibiotics, little is known about the variability of ... -
Cost-effectiveness of transdiagnostic group cognitive behavioural therapy for anxiety disorders versus treatment as usual : economic evaluation of a pragmatic randomized controlled trial over an 8-month time horizon using self-reported data
Other titre : Cost-effectiveness of transdiagnostic group cognitive behavioural therapy for anxiety disorders v. treatment as usual : economic evaluation of a pragmatic randomized controlled trial over an 8-month time horizon using self-reported data(2023)Abstract : Background: This economic evaluation supplements a pragmatic randomized controlled trial conducted in community care settings, which showed superior improvement in the symptoms of adults with anxiety disorders ... -
An examination of sudden gain prevalence across cognitive-behavioural therapy for anxiety and depressive disorders : a quantitative analysis and meta-analytic review
Other titre : Sudden gains in CBT for anxiety and depressive disorders(2023)Abstract : Sudden gains, incidences of unexpectedly large and stable session to session symptom reductions during psychotherapy, have been shown in samples of individuals receiving treatment for both anxiety and depressive ... -
The excessive carbon footprint of inhalers used in airway disease and its remedies
(2023)Abstract : The carbon footprint of human activities is a conversation topic worldwide. Many fields, including healthcare, have attempted to reduce their carbon footprint. For example, in Canada, 4.6% of greenhouse gases ... -
An analysis of differential improvement by diagnosis in group transdiagnostic cognitive behaviour therapy for anxiety disorders
(2023)Abstract : Introduction: Anxiety disorders are the most prevalent among the mental health disorders and have a negative impact on an individual’s life. CBT is documented as the most effective treatment for anxiety disorders. ... -
Measuring perceived barriers to physical activity in adolescents
(2015)Abstract : Background: Perceived barriers to moderate-to-vigorous physical activity (PA) may contribute to the low rates of moderate-to-vigorous PA in adolescents. We examined the psychometric properties of scores from the ... -
Sociodemographic factors and beliefs about medicines in the uptake of pharmacogenomic testing in older adults
Other titre : Sociodemographics and beliefs in PGx testing in older adults(2021)Abstract : Aim: To assess the impact of sociodemographic factors and beliefs about medicine on the uptake of pharmacogenomic (PGx) testing in older adults in a public healthcare system. Methods: Data is based on a sample ... -
Dissecting the expression landscape of cytochromes P450 in hepatocellular carcinoma: towards novel molecular biomarkers
(2019)Abstract: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths around the world. Recent advances in genomic technologies have allowed the identification of various molecular signatures in ... -
Current overview on viroid–host interactions
(2020)Abstract: Viroids are one of the most enigmatic highly structured, circular, single-stranded RNA phytopathogens. Although they are not known to code for any peptide, viroids induce visible symptoms in susceptible host ... -
In-line probing of RNA G-quadruplexes
(2013)Abstract: Although the majority of the initial G-quadruplex studies were performed on DNA molecules, there currently exists a rapidly growing interest in the investigation of those formed in RNA molecules that possess high ... -
Exploring mRNA 3'-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening
(2013)Abstract: Guanine-rich RNA sequences can fold into noncanonical, four stranded helical structures called G-quadruplexes that have been shown to be widely distributed within the mammalian transcriptome, as well as being ... -
New scoring system to identify RNA G-quadruplex folding
(2014)Abstract: G-quadruplexes (G4s) are non-canonical structures involved in many important cellular processes. To date, the prediction of potential G-quadruplex structures (PG4s) has been based almost exclusively on the ... -
Deep-sequencing of the Peach latent mosaic viroid reveals new aspects of population eterogeneity
(2014)Abstract: Viroids are small circular single-stranded infectious RNAs characterized by a relatively high mutation level. Knowledge of their sequence heterogeneity remains largely elusive and previous studies, using Sanger ... -
Tumor microenvironment–associated modifications of alternative splicing
(2014)Abstract: Pre-mRNA alternative splicing is modified in cancer, but the origin and specificity of these changes remain unclear. Here, we probed ovarian tumors to identify cancer-associated splicing isoforms and define the ... -
Elucidation of the structures of all members of the Avsunviroidae family
(2014)Abstract: Viroids are small single-stranded RNA pathogens which cause significant damage to plants. As their nucleic acids do not encode for any proteins, they are dependant solely on their structure for their propagation. ... -
Redirecting splicing with bifunctional oligonucleotides
(2014)Abstract: Ectopic modulators of alternative splicing are important tools to study the function of splice variants and for correcting mis-splicing events that cause human diseases. Such modulators can be bifunctional ... -
The folding of 5′-UTR human G-quadruplexes possessing a long central loop
(2014)Abstract: G-quadruplexes are widespread four-stranded structures that are adopted by G-rich regions of both DNA and RNA and are involved in essential biological processes such as mRNA translation. They are formed by the ... -
A conserved target site in HIV-1 Gag RNA is accessible to inhibition by both an HDV ribozyme and a short hairpin RNA
(2014)Abstract: Antisense-based molecules targeting HIV-1 RNA have the potential to be used as part of gene or drug therapy to treat HIV-1 infection. In this study, HIV-1 RNA was screened to identify more conserved and accessible ...
