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Alterations of the epigenome in brain cancer: loss of 5-hydroxymethylcytosine
Other titre : Altérations de l’épigénome dans le cancer du cerveau: perte de 5-hydroxyméthylcytosine
(Université de Sherbrooke, 2017)
Abstract : 5-Methylcytosine is an epigenetic mark, which can be oxidized to 5-hydroxymethylcytosine (5hmC) in DNA by ten-eleven translocation (TET) oxygenases. It is an initial step in the demethylation of 5mC. Levels of ...