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dc.contributor.authorBélanger, Guillaumefr
dc.contributor.authorDarsigny, Véroniquefr
dc.contributor.authorDoré, Michaelfr
dc.contributor.authorLévesque, Françoisfr
dc.date.accessioned2020-08-25T19:58:44Z
dc.date.available2020-08-25T19:58:44Z
dc.date.created2010fr
dc.date.issued2020-08-25
dc.identifier.urihttp://hdl.handle.net/11143/17296
dc.description.abstractAbstract: Although cycloadditions of azomethine ylides usually give mixtures of endo/exo adducts, we successfully tuned the mechanistic path of a new reaction cascade to afford substituted pyrrolidines in high yields and diastereomeric purity. This was achieved by forcing the demetalation of tin- or silicon-substituted iminium ions, followed by azomethine ylide cycloaddition and nucleophilic cyclization. Structural complexity is thus built rapidly in a fully controlled one-pot reaction cascade.fr
dc.language.isoengfr
dc.relation.isformatofhttps://doi.org/10.1021/ol902767bfr
dc.relation.ispartofISSN:1523-7052fr
dc.relation.ispartofOrganic Lettersfr
dc.rightsAttribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ca/*
dc.subjectPyrrolidinesfr
dc.subjectAdductsfr
dc.subjectCyclizationfr
dc.subjectAzomethinefr
dc.subjectMolecular structurefr
dc.titleHighly diastereoselective synthesis of substituted pyrrolidines using a sequence of azomethine ylide cycloaddition and nucleophilic cyclizationfr
dc.typeArticlefr
dc.rights.holder© ACS Journal Publishingfr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages1396-1399fr
udes.description.period12(7)fr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationBélanger, G., Darsigny, V., Doré, M., et Lévesque, F. (2010). "Highly diastereoselective synthesis of substituted pyrrolidines using a sequence of azomethine ylide cycloaddition and nucleophilic cyclization". Organic Letters, 12(7), 1396-1399. https://doi.org/10.1021/ol902767bfr
udes.description.sourceOrganic Lettersfr
udes.autorisation.depottruefr
udes.description.ordreauteursBélanger, Guillaume; Darsigny, Véronique; Doré, Michael; Lévesque, Françoisfr


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Attribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada
Except where otherwise noted, this document's license is described as Attribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada