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A Versatile cascade of intramolecular vilsmeier-haack and azomethine ylide 1,3-dipolar cycloaddition toward tricyclic cores of alkaloids

dc.contributor.authorLévesque, Françoisfr
dc.contributor.authorBélanger, Guillaumefr
dc.date.accessioned2020-08-24T20:42:23Z
dc.date.available2020-08-24T20:42:23Z
dc.date.created2008fr
dc.date.issued2020-08-24
dc.identifier.urihttp://hdl.handle.net/11143/17294
dc.description.abstractAbstract: In the pursuit of synthetic efficiency, we developed an innovative one-pot transformation of linear substrates into bi- and tricyclic adducts using a cascade of amide activation, nucleophilic cyclization, azomethine ylide generation, and subsequent inter- or intramolecular 1,3-dipolar cycloaddition. Despite the high density and variety of functional groups on the substrates, the sequence occurred with perfect chemoselectivity with good to excellent yields.fr
dc.language.isoengfr
dc.relation.isformatofhttps://doi.org/10.1021/ol802010nfr
dc.relation.ispartofISSN:1523-7052fr
dc.relation.ispartofOrganic Lettersfr
dc.rightsAttribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ca/*
dc.subjectEthersfr
dc.subjectAzomethinefr
dc.subjectOrganic compoundsfr
dc.subjectPrecursorsfr
dc.subjectCyclizationfr
dc.titleA Versatile cascade of intramolecular vilsmeier-haack and azomethine ylide 1,3-dipolar cycloaddition toward tricyclic cores of alkaloidsfr
dc.typeArticlefr
dc.rights.holder© ACS Journal Publishingfr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages4939-4942fr
udes.description.period10(21)fr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationLévesque, F. et Bélanger, G. (2008). "A Versatile cascade of intramolecular vilsmeier-haack and azomethine ylide 1,3-dipolar cycloaddition toward tricyclic cores of alkaloids". Organic Letters, 10(21), 4939-4942. https://doi.org/10.1021/ol802010nfr
udes.description.sourceOrganic Lettersfr
udes.autorisation.depottruefr
udes.description.ordreauteursLévesque, François; Bélanger, Guillaumefr


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Attribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada
Except where otherwise noted, this document's license is described as Attribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada