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Other titre : Plasma n-3 fatty acids in the elderly

dc.contributor.authorFortier, Mélaniefr
dc.contributor.authorTremblay-Mercier, Jenniferfr
dc.contributor.authorPlourde, Mélaniefr
dc.contributor.authorChouinard-Watkins, Raphaëlfr
dc.contributor.authorVandal, Milènefr
dc.contributor.authorPifferi, Fabienfr
dc.contributor.authorCunnane, Stephen
dc.contributor.authorFreemantle, Erikafr
dc.description.abstractThe elderly reportedly have a significantly higher % of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids in plasma and red cell lipids. However, these observations are from a few small studies and the health status of the elderly in these studies is for the most part unclear. Since the elderly are susceptible to cardiovascular and neurological illnesses that seem to be related in part to lower intake of n-3 fatty acids it seems paradoxical that their blood levels of EPA and DHA would be higher than in young adults. We report here plasma fatty acid profiles and their response to supplementation with two types of fish oils from several of our recent studies in the moderately healthy elderly. We define the moderately healthy elderly as those who were in good physical condition, had no cognitive decline and, if present, in whom hypothyroidism, hyperlipidemia and/or hypertension were well-controlled. As shown previously, we confirm the higher % EPA and % total n-3 fatty acids (but not DHA) in fasting plasma and extend these findings to include higher plasma concentrations (mg/L) of n-3 fatty acids as well. The EPA-predominant supplement raised DHA only in the young, whereas the DHA-predominant supplement raised EPA more in the young than in the elderly. The moderately healthy elderly clearly have higher plasma n-3 fatty acids but whether this reflects differences in intake versus aging-related changes in n-3 fatty acid metabolism remains to be
dc.relation.ispartofProstaglandins, Leukotrienes & Essential Fatty Acidsfr
dc.rightsAttribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada*
dc.subjectDocosahexaenoic acidfr
dc.subjectEicosapentaenoic acidfr
dc.subjectn-3 fatty acidfr
dc.titleHigher plasma n-3 fatty acid status in the moderately healthy elderly in southern Québec: higher fish intake or aging-related change in n-3 fatty acid metabolism?fr
dc.title.alternativePlasma n-3 fatty acids in the elderlyfr
dc.rights.holder© 2010 Elsevier
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationFortier, M., Tremblay-Mercier, J., Plourde, M., Chouinard-Watkins, R., Vandal, M., Pifferi, F., ... Cunnane, S. C. (2010). Higher plasma n-3 fatty acid status in the moderately healthy elderly in southern Québec: higher fish intake or aging-related change in n-3 fatty acid metabolism? ", 82(4-6), 277-280.
udes.description.sourceProstaglandins, Leukotrienes & Essential Fatty Acidsfr
udes.description.ordreauteursFortier, Mélanie; Tremblay-Mercier, Jennifer; Plourde, Mélanie; Chouinard-Watkins, Raphaël; Vandal, Milène; Pifferi, Fabien; Freemantle, Erika; Cunnane, Stephen

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Except where otherwise noted, this document's license is described as Attribution - Pas d’Utilisation Commerciale - Pas de Modification 2.5 Canada