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dc.contributor.authorBernier, Michaelfr
dc.contributor.authorBourgault, Patriciafr
dc.contributor.authorWhittingstall, Kevinfr
dc.contributor.authorLéonard, Guillaumefr
dc.contributor.authorLaroche, Sarahfr
dc.contributor.authorTousignant-Laflamme, Yannickfr
dc.contributor.authorLagueux, Emiliefr
dc.contributor.editorCentre de recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)fr
dc.contributor.editorÉcole de réadaptation, Université de Sherbrookefr
dc.contributor.otherMercier, Catherinefr
dc.date.accessioned2018-12-20T17:44:59Z
dc.date.available2018-12-20T17:44:59Z
dc.date.created2018fr
dc.date.issued2018-12-20
dc.identifierPMID:28654557fr
dc.identifier.urihttp://hdl.handle.net/11143/14487
dc.description.abstractBACKGROUND: The efficacy of graded motor imagery (GMI) for the management of complex regional pain syndrome (CRPS) is supported by evidence, but its treatment effect remains generally modest. Transcranial direct current stimulation (tDCS) has been advocated as an adjunct intervention to enhance the effect of motor imagery approaches in pain populations. OBJECTIVE: The purpose of this study was to investigate the effectiveness of GMI+active tDCS compared to the GMI+sham tDCS in the treatment of CRPS type I. METHODS: 22 patients (n=11/group) were randomly assigned to the experimental (GMI+tDCS) or placebo (GMI+sham tDCS) group. GMI treatments lasted 6 weeks; anodal tDCS was applied over the motor cortex for 5 consecutive days during the first 2 weeks and once a week thereafter. Changes in pain perception, quality of life, kinesiophobia, pain catastrophizing, anxiety and mood were monitored after 6 weeks of treatment (T1) and 1-month post treatment (T2). RESULTS: GMI+tDCS induced no statistically significant reduction in pain compared to GMI+sham tDCS. Although we observed significant group differences in kinesiophobia (P=0.012), pain catastrophizing (P=0.049) and anxiety (P=0.046) at T1, these improvements were not maintained at T2 and did not reached a clinically significant difference. DISCUSSION: We found no added value of tDCS combined with GMI treatments for reducing pain in patients with chronic CRPS. However, given that GMI+sham tDCS induced no significant change, further studies comparing GMI+tDCS and tDCS alone are needed to further document tDCS's effect in CRPS.fr
dc.language.isoengfr
dc.relation.isformatofhttps://doi.org/10.1097/AJP.0000000000000522fr
dc.relation.ispartofISSN:1536-5409fr
dc.relation.ispartofThe Clinical Journal of Painfr
dc.subjectComplex regional pain syndromefr
dc.subjectNon-invasive brain stimulationfr
dc.subjectGraded motor imageryfr
dc.subjectPain managementfr
dc.titleThe effectiveness of transcranial direct current stimulation as an add-on modality to graded motor imagery for treatment of complex regional pain syndrome: A randomized proof of concept studyfr
dc.typeArticlefr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.pages145-154fr
udes.description.period34(2)fr
udes.description.sponsorshipCanadian Pain Society (CPS)fr
udes.description.sponsorshipQuebec Pain Research Network (QPRN)fr
udes.description.sponsorshipInflammation and Pain Axisfr
udes.description.sponsorshipFonds de recherche Québec – Santé (FRQS)fr
udes.description.sponsorshipCanada Research Chairs (CRC)fr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationLagueux É, Bernier M, Bourgault P, Whittingstall K, Mercier C, Léonard G, … Tousignant-Laflamme Y. (2018). The Effectiveness of Transcranial Direct Current Stimulation as an Add-on Modality to Graded Motor Imagery for Treatment of Complex Regional Pain Syndrome: A Randomized Proof of Concept Study. Clin J Pain. 34(2), 145-154. https://doi.org/10.1097/AJP.0000000000000522fr
udes.description.sourceThe Clinical Journal of Painfr
udes.autorisation.depottruefr
udes.description.ordreauteursLagueux, Emilie; Bernier, Michael; Bourgault, Patricia; Whittingstall, Kevin; Mercier, Catherine; Léonard, Guillaume; Laroche, Sarah; Tousignant-Laflamme, Yannickfr


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