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dc.contributor.authorMartel, Maryliefr
dc.contributor.authorHarvey, Marie-Philippefr
dc.contributor.authorHoude, Francisfr
dc.contributor.authorBalg, Frédéricfr
dc.contributor.authorGoffaux, Philippefr
dc.contributor.authorLéonard, Guillaumefr
dc.contributor.editorInstitut universitaire de gériatrie de Sherbrooke. Centre de recherche sur le vieillissementfr
dc.contributor.editorUniversité de Sherbrooke. Faculté de médecine et des sciences de la santéfr
dc.date.accessioned2017-03-14T18:32:31Z
dc.date.available2017-03-14T18:32:31Z
dc.date.created2017fr
dc.date.issued2017-03-14
dc.identifierPMID:28188330fr
dc.identifier.urihttp://hdl.handle.net/11143/10186
dc.description.abstractAbstract : The interaction between pain and the motor system is well-known, with past studies showing that pain can alter corticomotor excitability and have deleterious effects on motor learning. The aim of this study was to better understand the cortical mechanisms underlying the interaction between pain and the motor system. Experimental pain was induced on 19 young and healthy participants using capsaicin cream, applied on the middle volar part of the left forearm. The effect of pain on brain activity and on the corticomotor system was assessed with electroencephalography (EEG) and transcranial magnetic stimulation (TMS), respectively. Compared to baseline, resting state brain activity significantly increased after capsaicin application in the central cuneus (theta frequency), left dorsolateral prefrontal cortex (alpha frequency), and left cuneus and right insula (beta frequency). A pain-evoked increase in the right primary motor cortex (M1) activity was also observed (beta frequency), but only among participants who showed a reduction in corticospinal output (as depicted by TMS recruitment curves). These participants further showed greater beta M1-cuneus connectivity than the other participants. These findings indicate that pain-evoked increases in M1 beta power are intimately tied to changes in the corticospinal system, and provide evidence that beta M1-cuneus connectivity is related to the corticomotor alterations induced by pain. The differential pattern of response observed in our participants suggest that the effect of pain on the motor system is variable from on individual to another; an observation that could have important clinical implications for rehabilitation professionals working with pain patients.fr
dc.language.isoengfr
dc.relation.isformatofdoi:10.1007/s00221-017-4880-0fr
dc.relation.ispartofISSN:0014-4819fr
dc.relation.ispartofExperimental brain researchfr
dc.subjectCorticospinal tractfr
dc.subjectElectroencephalographyfr
dc.subjectExperimental painfr
dc.subjectFunctional connectivityfr
dc.subjectMotor cortexfr
dc.subjectPainfr
dc.subjectRecruitment curvesfr
dc.subjectTranscranial magnetic stimulationfr
dc.titleUnravelling the effect of experimental pain on the corticomotor system using transcranial magnetic stimulation and electroencephalography.fr
dc.typeArticlefr
dc.rights.holder© Springer Verlag 2017fr
udes.description.typestatusPost-publicationfr
udes.description.typepubRévisé et accepté par des pairsfr
udes.description.sponsorshipCRSNGfr
udes.description.diffusionDiffusé par Savoirs UdeS, le dépôt institutionnel de l'Université de Sherbrookefr
dc.identifier.bibliographicCitationMartel, M., Harvey, M.-P., Houde, F., Balg, F., Goffaux, P., Léonard, G. (2017). Unravelling the effect of experimental pain on the corticomotor system using transcranial magnetic stimulation and electroencephalography. Experimental brain research, Feb. 10. doi:10.1007/s00221-017-4880-0. [Epub ahead of print]fr
udes.description.sourceExperimental brain researchfr
udes.autorisation.depottruefr
udes.description.ordreauteursMartel, Marylie; Harvey, Marie-Philippe; Houde, Francis; Balg, Frédéric; Goffaux, Philippe; Léonard, Guillaumefr


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