Now showing documents 1-10 of 18
Physiological and comparative evidence fails to confirm an adaptive role for aging in evolution
Abstract: The longstanding debate about whether aging may have evolved for some adaptive reason is generally considered to pit evolutionary theory against empirical observations consistent with aging as a programmed aspect ...
Inflamm‐aging does not simply reflect increases in pro‐inflammatory markers
Abstract: Many biodemographic studies use biomarkers of inflammation to understand or predict chronic disease and aging. Inflamm-aging, i.e. chronic low-grade inflammation during aging, is commonly characterized by ...
A novel statistical approach shows evidence for multi-system physiological dysregulation during aging
Other titre : A novel measurement approach and evidence for multi-system physiological dysregulation during aging
Abstract: Previous studies have identified many biomarkers that are associated with aging and related outcomes, but the relevance of these markers for underlying processes and their relationship to hypothesized systemic ...
Transcranial magnetic stimulation measures in the elderly: reliability, smallest detectable change and the potential influence of lifestyle habits
Background: Transcranial magnetic stimulation (TMS) is a non-invasive technique that can be used to evaluate cortical function and corticospinal pathway in normal and pathological aging. Yet, the metrologic properties of ...
Higher plasma n-3 fatty acid status in the moderately healthy elderly in southern Québec: higher fish intake or aging-related change in n-3 fatty acid metabolism?
Other titre : Plasma n-3 fatty acids in the elderly
The elderly reportedly have a significantly higher % of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids in plasma and red cell lipids. However, these observations are from a few small studies and the health status ...
Omega-3 PUFA metabolism and brain modifications during aging
In Canada, 5.5 million (16% of Canadians) adults are >65 years old and projections suggest this number will be approximately 20% of Canadians by 2024. A major concern regarding old age is a decline in health, especially ...
Aging, cognitive decline, apolipoprotein E and docosahexaenoic acid metabolism
Au Canada, 17 millions d’adultes âgés entre 30–64 ans pourraient bénéficier d’une intervention en prévention pour diminuer leur risque de développer la maladie d’Alzheimer (MA). L’un des groupes les plus à risque de ...
Eicosapentaenoic acid decreases postprandial β-hydroxybutyrate and free fatty acid responses in healthy young and elderly
Other titre : Eicosapentaenoic acid decreases postprandial beta-hydroxybutyrate and free fatty acid responses in healthy young and elderly
Objectives: We investigated whether a dietary supplement rich in eicosapentaenoic acid (EPA) increases fasting plasma ketones or postprandial ketone responses in healthy young and elderly subjects. Methods: Ten young ...
Challenges to determining whether DHA can protect against age-related cognitive decline
DHA, an omega-3 fatty acid, is an important constituent of brain membranes and has a key role in brain development and function. This review aims to highlight recent research on DHA’s role during age-related cognitive ...
Fish, docosahexaenoic acid and Alzheimer’s disease
Cognitive decline in the elderly, particularly Alzheimer’s disease (AD), is a major socio-economic and healthcare concern. We review here the literature on one specific aspect of diet affecting AD, that of the ω3 fatty ...