Now showing documents 1-10 of 31
Aging, cognitive decline, apolipoprotein E and docosahexaenoic acid metabolism
Au Canada, 17 millions d’adultes âgés entre 30–64 ans pourraient bénéficier d’une intervention en prévention pour diminuer leur risque de développer la maladie d’Alzheimer (MA). L’un des groupes les plus à risque de ...
Higher plasma n-3 fatty acid status in the moderately healthy elderly in southern Québec: higher fish intake or aging-related change in n-3 fatty acid metabolism?
Other titre : Plasma n-3 fatty acids in the elderly
The elderly reportedly have a significantly higher % of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids in plasma and red cell lipids. However, these observations are from a few small studies and the health status ...
Absorption and metabolism of conjugated α-linolenic acid given as free fatty acids or triacylglycerols in rats
Background: Conjugated linoleic acid (CLA) is a group of polyunsaturated fatty acids which have been extensively studied in the past two decades. However, conjugated octadecatrienoic acid such as cis-9,trans-11,cis-15 ...
Conjugated linoleic acid supplementation for 8 weeks fails to impact body composition, lipid profile, or safety parameters in overweight, hyperlipidemic men
Other titre : Conjugated linoleic acid supplementation for 8 weeks does not affect body composition, lipid profile, or safety biomarkers in overweight, hyperlipidemic men
The usefulness of conjugated linoleic acid (CLA) as a nutraceutical remains ambiguous. Our objective was, therefore, to investigate the effect of CLA on body composition, blood lipids, and safety biomarkers in overweight, ...
Plasma omega-3 fatty acid response to a fish oil supplement in the healthy elderly
Other titre : Plasma response to fish oil in the elderly
Little information is available concerning whether incorporation of dietary omega-3 fatty acids into plasma lipids changes during healthy aging. Elderly (74 ± 4 years old) and young (24 ± 2 years old) adults were given a ...
Docosahexaenoic acid and shore‐based diets in hominin encephalization: A rebuttal
Other titre : Fish and human brain evolution
Carlson and Kingston (: Am J Hum Biol 19:132–141) propose that preformed dietary docosahexaenoic acid (an omega-3 fatty acid in fish) did not have a significant role in hominin encephalization. Their position hinges ...
Kinetics of 13C-DHA before and during fish-oil supplementation in healthy older individuals
Background: Docosahexaenoic acid (DHA) kinetics appear to change with intake, which is an effect that we studied in an older population by using uniformly carbon-13–labeled DHA (13C-DHA). Objective: We evaluated the ...
Postprandial enrichment of triacylglycerol-rich lipoproteins with omega-3 fatty acids: lack of an interaction with apolipoprotein E genotype?
Background: We have previously demonstrated that carrying the apolipoprotein (apo) E epsilon 4 (E4+) genotype disrupts omega-3 fatty acids (n − 3 PUFA) metabolism. Here we hypothesise that the postprandial clearance of n ...
Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Is It Contributing to Higher Risk of Cognitive Decline and Coronary Heart Disease?
Apolipoprotein E (ApoE) is a protein playing a pivotal role in lipid homeostasis since it regulates cholesterol, triglyceride and phospholipid metabolism in the blood and the brain. APOE gene regulates the expression of ...
Apolipoprotein E isoforms disrupt long-chain fatty acid distribution in the plasma, the liver and the adipose tissue of mice
Evidences suggest that omega-3 fatty acid (n-3 PUFA) metabolism is imbalanced in apolipoprotein E epsilon 4 isoform carriers (APOE4). This study aimed to investigate APOE genotype-dependant modulation of FA profiles, protein ...