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AuthorPlourde, Mélanie (10)Cunnane, Stephen C. (9)Tremblay-Mercier, Jennifer (4)Vandal, Milène (4)Camden, Chantal (3)... View MoreSubjectDocosahexaenoic acid (5)Eicosapentaenoic acid (5)Arachidonic acid (4)Metabolism (4)Brain (3)... View MorePublication date2009 (9)2008 (6)2007 (3)2006 (1)2005 (1)Types of document
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Plasma n-3 fatty acid response to an n-3 fatty acid supplement is modulated by apoE ɛ4 but not by the common PPAR-α L162V polymorphism in men

Plourde, Mélanie; Vohl, Marie-Claude; Vandal, Milène; Couture, Patrick; Lemieux, Simone; Cunnane, Stephen C.. (2009)
The risk of Alzheimer's disease is increased for carriers of apoE4 (E4) or the PPAR-α L162V polymorphism (L162V), but it is decreased in fish and seafood consumers. The link between high fish intake and reduced risk of ...
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Docosahexaenoic acid and shore‐based diets in hominin encephalization: A rebuttal
Other titre : Fish and human brain evolution

Cunnane, Stephen C.; Plourde, Mélanie; Stewart, Kathy; Crawford, Michel A. (2007)
Carlson and Kingston ([2007]: Am J Hum Biol 19:132–141) propose that preformed dietary docosahexaenoic acid (an omega-3 fatty acid in fish) did not have a significant role in hominin encephalization. Their position hinges ...
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Plasma omega-3 fatty acid response to a fish oil supplement in the healthy elderly
Other titre : Plasma response to fish oil in the elderly

Vandal, Milène; Freemantle, Erika; Tremblay-Mercier, Jennifer; Plourde, Mélanie; Fortier, Mélanie; Bruneau, Joannie; Gagnon, Johannie; Bégin, Michel; Cunnane, Stephen, C. (2008)
Little information is available concerning whether incorporation of dietary omega-3 fatty acids into plasma lipids changes during healthy aging. Elderly (74 ± 4 years old) and young (24 ± 2 years old) adults were given a ...
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Fish, docosahexaenoic acid and Alzheimer’s disease

Cunnane, Stephen C.; Plourde, Mélanie; Pifferi, Fabien; Bégin, Michael E.; Féart, Catherine; Barberger-Gateau, Pascale (2009)
Cognitive decline in the elderly, particularly Alzheimer’s disease (AD), is a major socio-economic and healthcare concern. We review here the literature on one specific aspect of diet affecting AD, that of the ω3 fatty ...
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Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements

Plourde, Mélanie; Cunnane, Stephen C. (2007)
La communauté scientifique accorde beaucoup d’intérêt à plusieurs acides gras polyinsaturés (PUFA) et à leur atténuation potentielle du taux de mortalité et de morbidité causée par les maladies dégénératives du système ...
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Absorption and metabolism of conjugated α-linolenic acid given as free fatty acids or triacylglycerols in rats

Plourde, Mélanie; Sergiel, Jean-Pierre; Chardigny, Jean-Michel; Grégoire, Stéphane; Angers, Paul; Sébédio, Jean-Louis (2006)
Background: Conjugated linoleic acid (CLA) is a group of polyunsaturated fatty acids which have been extensively studied in the past two decades. However, conjugated octadecatrienoic acid such as cis-9,trans-11,cis-15 ...
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Metabolic response to a ketogenic breakfast in the healthy elderly.

Freemantle, Erika; Vandal, Milène; Tremblay-Mercier, Jennifer; Plourde, Mélanie; Desgagné, J.; Ryan, MA.; Fortier, Mélanie; Poirier, J.; Cunnane, Stephen C. (2009)
OBJECTIVE: To determine whether the metabolism of glucose or ketones differs in the healthy elderly compared to young or middle-aged adults during mild, short-term ketosis induced by a ketogenic breakfast. DESIGN AND ...
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Linking low docosahexaenoic acid intake to Alzheimer's disease : caution recommended

Cunnane, Stephen C.; Plourde, Mélanie; Vandal, Milène; Freemantle, Erika; Tremblay-Mercier, Jennifer; Bégin, Michel (2007)
Prospective cohort studies and animal models support the concept that low docosahexaenoic acid intake is implicated in the etiology or progression of Alzheimer’s disease. However, other studies crucial to this relationship ...
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Eicosapentaenoic acid decreases postprandial β-hydroxybutyrate and free fatty acid responses in healthy young and elderly
Other titre : Eicosapentaenoic acid decreases postprandial beta-hydroxybutyrate and free fatty acid responses in healthy young and elderly

Plourde, Mélanie; Tremblay-Mercier, Jennifer; Fortier, Mélanie; Pifferi, Fabien; Cunnane, Stephen C. (2009)
Objectives: We investigated whether a dietary supplement rich in eicosapentaenoic acid (EPA) increases fasting plasma ketones or postprandial ketone responses in healthy young and elderly subjects. Methods: Ten young ...
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Conjugated linoleic acids: why the discrepancy between animal and human studies?

Plourde, Mélanie; Jew, Stephanie; Cunnane, Stephen C.; Jones, Peter J. H. (2008)
Conjugated linoleic acids (CLA) are positional and geometric isomers of linoleic acid. In animals, CLA consumption reduces body fat but results in humans are less conclusive. This review of the literature on CLA and loss ...
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